Genistein is an isoflavone, a naturally occurring chemical found in soy beans, legumes and red clover. It is similar in structure to the hormone oestrogen and is used to regulate hormone activity and treat symptoms of menopause. There is some evidence that genistein may have chemopreventative and therapeutic effects on certain types of cancer [1, 2].
Following four years of intensive research, our scientists have developed an enhanced formulation of genistein that has demonstrated improved dissolution and disintegration times compared to similar products. This means that the genistein is more readily absorbed into the bloodstream and can perform more effectively.
In vitro and in vivo studies have found that isoflavones perform well against hormone-related cancers when combined with chemotherapeutic agents. Genistein is found to be analogous to 17β-oestradiol and has 4% binding affinity for oestrogen receptor-alpha and 87% for oestrogen receptor-beta. When 17β-oestradiol is connected to these receptors, cancer progression starts. Therefore, when genistein is introduced to the body, cancer progression can be inhibited as it replaces the action of 17β-oestradiol.
In our bioavailability studies, we compared the pharmacokinetics of our formulation of genistein compared with a similar product available on the market. We found that the maximum concentration of our product was 34% higher with 10% higher AUC. This represents a significantly higher maximum observed plasma concentration and a slight but important increase in exposure. The full study, Genistein as a dietary supplement; formulation, analysis and pharmacokinetic study, can be read here (plos.org)
Genistein has been developed in our ISO 22000-certified facilities in Europe following the strictest guidelines of pharmacopoeia usually reserved for the development of medicinal drugs.
Do not take this product if you are pregnant or nursing. Consult your healthcare provider before use if you are taking any prescription medications or have a medical condition. Discontinue use if unusual symptoms occur.
If you are placing an order with us from outside Europe (including Russia), we recommend that you place a minimum order of three products due to shipping costs. This is not mandatory.
For high-volume orders of 100 bottles or more, please email orders@wel-nutra.com. We dispatch all products through one of our trusted shipping partners, on dispatch you will receive an email with tracking information to enable you to track your order. Please note it is the customer’s responsibility to track the shipment and pay any customs and import duties required. If an order is returned to us we will refund to you the order cost, however the cost of shipping will not be refunded. A new order should be placed on Wel-Nutra
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